The distribution of metastases in the spine varies: It is not entirely understood how MBD spreads, but its propensity for the spine is considered to be due to haematogenous spread via the venous or arterial pathways. The five types of cancer that are most likely to spread to the spine are: The spine is often one of the earliest areas affected, particularly in patients who have a history of breast and prostate cancer. Bone is a common location for metastases (ie cancers that have spread from primary cancer to a new site in the body).Is the second most common serious spinal pathology - a vertebral fracture is the most common. Introduction to Spinal Malignancy Ä«etween one and five percent of all musculoskeletal presentations in primary care are due to serious pathology and these rates are expected to increase as cancer survival rates improve. 3 Risk of Developing Metastatic Bone Disease.
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